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A Peristaltic Pump Driven Zr-89 Separation Module

Author

  • Jonathan Siikanen
  • Mikael Peterson
  • T. A. Tran
  • Per Roos
  • Tomas G Ohlsson
  • Anders Sandell

Summary, in English

To facilitate the separation of Zr-89 produced in yttrium foils, an automated separation module was designed and assembled. The module separates more than 85% of produced Zr-89 - activity in 3 g foils in less than 90 min. About 10 % remains in the dissolving vial. The quality of the separated Zr-89 activity was investigated for labeling of the HER2-binding monoclonal antibody fragment, trastuzumab-Fab.

Publishing year

2012

Language

English

Pages

206-210

Publication/Series

14th International Workshop on Targetry and Target Chemistry

Volume

1509

Links

Document type

Conference paper

Publisher

American Institute of Physics (AIP)

Topic

  • Radiology and Medical Imaging

Keywords

  • Zr-89
  • PET
  • Separation Module
  • Automation

Conference name

14th International Workshop on Targetry and Target Chemistry (WTTC)

Conference date

2012-08-26 - 2012-08-29

Conference place

Playa del Carmen, Mexico

Status

Published

ISBN/ISSN/Other

  • ISSN: 1551-7616
  • ISSN: 0094-243X