Protein Phosphorylation

Faculty of Medicine / Department of Experimental Medical Science

Fax number: +46 46 222 40 22

Visiting address: Sölvegatan 19, BMC C11, 221 84 Lund

Description

An overall aim of our research is to study the regulation and function of protein phosphorylation cascades with relevance to type 2 diabetes, with a particular focus on adipose tissue, since this tissue is involved in the pathogenesis of diabetes. Presently, our main project evolves around the amp-activated protein kinase (ampk) family, which consists of ampk and another 12 related kinases, of which we are particularly interested in the salt-inducible kinases (1-3). We have shown that sik2 is down-regulated in adipose tissue from obese individuals and are currently investigating the role of sik2 in the development of diabetes. Ampk is a target for new and existing diabetes therapy, and our research will predict effects of such therapy in adipose tissue.

Staff

G

Olga Göransson

Research team manager, Principal investigator, Professor

olga [dot] goransson [at] med [dot] lu [dot] se

+46 46 222 95 52

L

Maria Lindahl

Research engineer

maria [dot] lindahl [at] med [dot] lu [dot] se

+46 46 222 08 78

N

Florentina Negoita

Visiting research fellow

florentina [dot] negoita [at] med [dot] lu [dot] se

+46 46 222 95 52

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